Retrospective analysis of 10,000 implants from insertion up to 20 years—analysis of implantations using augmentative procedures
Identifieur interne : 000540 ( Main/Exploration ); précédent : 000539; suivant : 000541Retrospective analysis of 10,000 implants from insertion up to 20 years—analysis of implantations using augmentative procedures
Auteurs : Wolfram Knöfler [Allemagne] ; Thomas Barth [Allemagne] ; Reinhard Graul [Allemagne] ; Dietmar Krampe [Allemagne]Source :
- International Journal of Implant Dentistry [ 2198-4034 ] ; 2016.
Abstract
A sufficient amount of bone is essential to ensure long-term stability of dental implants. To support the bone regeneration process, different techniques and materials are available. It has been questioned whether these techniques and materials may compromise implant survival compared to pristine bone. To properly answer this question, long-term stability up to 20.2 years after insertion of implants placed in augmented or non-augmented sites was retrospectively analysed.
Retrospective analysis included 10,158 implants from 3095 patients in three private practices who underwent implant therapy with or without bone augmentation procedures. Different graft materials and membranes were used for augmentation. If necessary, the graft was stabilised using a titanium mesh. Implant survival was evaluated analysing explantation rates and Kaplan-Meier survival curves in augmented or non-augmented sites. In additional subgroup analyses, augmentation procedures, graft materials and membranes were compared applying descriptive statistics.
The observation period varied from the day of implantation up to 20.2 years after implant insertion. The overall implant survival was 95.5% (augmented sites 96.33%; native sites 94.27%). Comparison of Kaplan-Meier survival curves revealed significantly better survival of implants in augmented sites (
The retrospective analysis shows that implants inserted in augmented or native bone demonstrate similar implant survival under the conditions of private practice compared to prospective studies. To establish a broad base of support, further well-designed clinical trials are necessary.
Url:
DOI: 10.1186/s40729-016-0061-3
PubMed: 27915417
PubMed Central: 5136376
Affiliations:
- Allemagne
- Bade-Wurtemberg, District de Karlsruhe, District de Leipzig, Saxe (Land)
- Leipzig, Mannheim
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Zahnärztliches Kompetenzzentrum GmbH, Prager Strasse 4, 04103 Leipzig, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Dentale - Zahnärztliches Kompetenzzentrum GmbH, Prager Strasse 4, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Graul, Reinhard" sort="Graul, Reinhard" uniqKey="Graul R" first="Reinhard" last="Graul">Reinhard Graul</name><affiliation wicri:level="3"><nlm:aff id="Aff3">Gemeinschaftspraxis für Mund-/Kiefer-/Gesichtschirurgie & Zahnheilkunde, Biedermannstr. 9-13, 04277 Leipzig, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Gemeinschaftspraxis für Mund-/Kiefer-/Gesichtschirurgie & Zahnheilkunde, Biedermannstr. 9-13, 04277 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Krampe, Dietmar" sort="Krampe, Dietmar" uniqKey="Krampe D" first="Dietmar" last="Krampe">Dietmar Krampe</name><affiliation wicri:level="3"><nlm:aff id="Aff4">DENTSPLY Implants, Steinzeugstraße 50, 68229 Mannheim, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>DENTSPLY Implants, Steinzeugstraße 50, 68229 Mannheim</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Mannheim</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27915417</idno><idno type="pmc">5136376</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136376</idno><idno type="RBID">PMC:5136376</idno><idno type="doi">10.1186/s40729-016-0061-3</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000C84</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000C84</idno><idno type="wicri:Area/Pmc/Curation">000C84</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000C84</idno><idno type="wicri:Area/Pmc/Checkpoint">000474</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000474</idno><idno type="wicri:Area/Ncbi/Merge">006C60</idno><idno type="wicri:Area/Ncbi/Curation">006C60</idno><idno type="wicri:Area/Ncbi/Checkpoint">006C60</idno><idno type="wicri:Area/Main/Merge">000540</idno><idno type="wicri:Area/Main/Curation">000540</idno><idno type="wicri:Area/Main/Exploration">000540</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Retrospective analysis of 10,000 implants from insertion up to 20 years—analysis of implantations using augmentative procedures</title><author><name sortKey="Knofler, Wolfram" sort="Knofler, Wolfram" uniqKey="Knofler W" first="Wolfram" last="Knöfler">Wolfram Knöfler</name><affiliation wicri:level="3"><nlm:aff id="Aff1">Praxis für Mund-, Kiefer-, Gesichtschirurgie und Implantologie, Rietschelstr. 27, 04177 Leipzig, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Praxis für Mund-, Kiefer-, Gesichtschirurgie und Implantologie, Rietschelstr. 27, 04177 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Barth, Thomas" sort="Barth, Thomas" uniqKey="Barth T" first="Thomas" last="Barth">Thomas Barth</name><affiliation wicri:level="3"><nlm:aff id="Aff2">Dentale - Zahnärztliches Kompetenzzentrum GmbH, Prager Strasse 4, 04103 Leipzig, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Dentale - Zahnärztliches Kompetenzzentrum GmbH, Prager Strasse 4, 04103 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Graul, Reinhard" sort="Graul, Reinhard" uniqKey="Graul R" first="Reinhard" last="Graul">Reinhard Graul</name><affiliation wicri:level="3"><nlm:aff id="Aff3">Gemeinschaftspraxis für Mund-/Kiefer-/Gesichtschirurgie & Zahnheilkunde, Biedermannstr. 9-13, 04277 Leipzig, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Gemeinschaftspraxis für Mund-/Kiefer-/Gesichtschirurgie & Zahnheilkunde, Biedermannstr. 9-13, 04277 Leipzig</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Leipzig</region><settlement type="city">Leipzig</settlement></placeName></affiliation></author><author><name sortKey="Krampe, Dietmar" sort="Krampe, Dietmar" uniqKey="Krampe D" first="Dietmar" last="Krampe">Dietmar Krampe</name><affiliation wicri:level="3"><nlm:aff id="Aff4">DENTSPLY Implants, Steinzeugstraße 50, 68229 Mannheim, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>DENTSPLY Implants, Steinzeugstraße 50, 68229 Mannheim</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Mannheim</settlement></placeName></affiliation></author></analytic><series><title level="j">International Journal of Implant Dentistry</title><idno type="eISSN">2198-4034</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>A sufficient amount of bone is essential to ensure long-term stability of dental implants. To support the bone regeneration process, different techniques and materials are available. It has been questioned whether these techniques and materials may compromise implant survival compared to pristine bone. To properly answer this question, long-term stability up to 20.2 years after insertion of implants placed in augmented or non-augmented sites was retrospectively analysed.</p></sec><sec><title>Methods</title><p>Retrospective analysis included 10,158 implants from 3095 patients in three private practices who underwent implant therapy with or without bone augmentation procedures. Different graft materials and membranes were used for augmentation. If necessary, the graft was stabilised using a titanium mesh. Implant survival was evaluated analysing explantation rates and Kaplan-Meier survival curves in augmented or non-augmented sites. In additional subgroup analyses, augmentation procedures, graft materials and membranes were compared applying descriptive statistics.</p></sec><sec><title>Results</title><p>The observation period varied from the day of implantation up to 20.2 years after implant insertion. The overall implant survival was 95.5% (augmented sites 96.33%; native sites 94.27%). Comparison of Kaplan-Meier survival curves revealed significantly better survival of implants in augmented sites (<italic>p</italic> = 0.0025). When comparing different augmentation procedures, the best results were found for bone condensing followed by lateral augmentation. Graft materials were used in 58.2%, membranes in 36.6% of all implant sites. The most often used graft materials were a deproteinized bovine bone mineral (53.0%) and autogenous bone particles (32.5%). Both provided the best results and showed a significantly better implant survival compared to no graft material using the Kaplan-Meier method (<italic>p</italic> = 0.0104 and <italic>p</italic> < 0.0001). A native collagen membrane was used most often (74.0% of the membrane sites) and provided the best results regarding implant survival in the log-rank test.</p></sec><sec><title>Conclusions</title><p>The retrospective analysis shows that implants inserted in augmented or native bone demonstrate similar implant survival under the conditions of private practice compared to prospective studies. 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Darius</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Buch, Rs" uniqKey="Buch R">RS Buch</name></author><author><name sortKey="Weibrich, G" uniqKey="Weibrich G">G Weibrich</name></author><author><name sortKey="Wagner, W" uniqKey="Wagner W">W Wagner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Derks, J" uniqKey="Derks J">J Derks</name></author><author><name sortKey="Hakansson, J" uniqKey="Hakansson J">J Hakansson</name></author><author><name sortKey="Wennstrom, Jl" uniqKey="Wennstrom J">JL Wennstrom</name></author><author><name sortKey="Tomasi, C" uniqKey="Tomasi C">C Tomasi</name></author><author><name sortKey="Larsson, M" uniqKey="Larsson M">M Larsson</name></author><author><name sortKey="Berglundh, T" uniqKey="Berglundh T">T Berglundh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alsaadi, G" uniqKey="Alsaadi G">G Alsaadi</name></author><author><name sortKey="Quirynen, M" uniqKey="Quirynen M">M Quirynen</name></author><author><name sortKey="Komarek, A" uniqKey="Komarek A">A Komarek</name></author><author><name sortKey="Van Steenberghe, D" uniqKey="Van Steenberghe D">D van Steenberghe</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Montes, Cc" uniqKey="Montes C">CC Montes</name></author><author><name sortKey="Pereira, Fa" uniqKey="Pereira F">FA Pereira</name></author><author><name sortKey="Thome, G" uniqKey="Thome G">G Thome</name></author><author><name sortKey="Alves, Ed" uniqKey="Alves E">ED Alves</name></author><author><name sortKey="Acedo, Rv" uniqKey="Acedo R">RV Acedo</name></author><author><name sortKey="De Souza, Jr" uniqKey="De Souza J">JR de Souza</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>Bade-Wurtemberg</li><li>District de Karlsruhe</li><li>District de Leipzig</li><li>Saxe (Land)</li></region><settlement><li>Leipzig</li><li>Mannheim</li></settlement></list><tree><country name="Allemagne"><region name="Saxe (Land)"><name sortKey="Knofler, Wolfram" sort="Knofler, Wolfram" uniqKey="Knofler W" first="Wolfram" last="Knöfler">Wolfram Knöfler</name></region><name sortKey="Barth, Thomas" sort="Barth, Thomas" uniqKey="Barth T" first="Thomas" last="Barth">Thomas Barth</name><name sortKey="Graul, Reinhard" sort="Graul, Reinhard" uniqKey="Graul R" first="Reinhard" last="Graul">Reinhard Graul</name><name sortKey="Krampe, Dietmar" sort="Krampe, Dietmar" uniqKey="Krampe D" first="Dietmar" last="Krampe">Dietmar Krampe</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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